Motility patterns– Peristalsis– Peristalsis is a reflex response that is initiated when the gut wall is stretched by the contents of the lumen, and it occurs in all parts of the gastrointestinal tract from the oesophagus to the rectum. The stretch initiates a circular contraction behind the stimulus and an area of relaxation in front of it The wave of contraction then moves in an oral-to-caudal direction, propelling the contents of the lumen forward at rates that vary from 2 to 25 cm/s. Peristaltic activity can be increased or decreased by the autonomic input to the gut, but its occurrence … Continue reading Neural regulation of GIT
GERD is a esophagogastric junction disorder where there is efflux of gastric contents due to laxity in LES Continue reading GERD- gastro-oesophagial reflux disease
a phase 2 trial using tranglutaminase 2 inhibitor in celiac disease significant improvement in villous height to crypt depth among intervention group compared to placebo group. Continue reading A potential cure for celiac disease! promising results in a Phase 2 RCT.
The American college of gastroenterology had published the latest UGIB guidelines in January 2021. Although much has not changed, they have considered new evidence from RCT’s published in the last 5 years to make these recommendations. Continue reading Upper G.I bleeding- ACG clinical guideline update.
SARS-CoV2, first started at Wuhan province, china has spread throughout the world, leading to a pandemic, the science here is evolving daily, with new molecules discovered every day and scientists scrambled to investigate new therapies. Continue reading Covid 19 treatment- facts and myths uncovered!
we all know the patients with GERD, most of them are dependant on Proton pump inhibitors (PPI), there are surgeries for these patients who have inadequate response to PPI, how ever, their symptoms usually relapse after 5 to 10 years of surgery. Continue reading A Novel therapy for GERD! data from single centre study shows promising results.
The gastric acid production plays a key role in plasma iron homeostasis.
To be absorbed, iron must be in the ferrous (Fe2+) state or bound by a protein such as heme. Continue reading Iron Absorption
Development- They develop at various sites during embryonic periods. Initially yolk sac produces them, then later placenta. During second and third trimester the site shifts to bone marrow and spleen. Yolk sac- produces embryonic hemoglobin and tissue resident macrophages. intraembryonic … Continue reading Physiology of red cell production
Download PDF file Continue reading HIV notes
Usually self-limited illness.
Symptoms- nausea, vomiting, abdominal pain, jaundice.
Incubation period- 15 to 50 days Continue reading Hepatitis A